One reason is being low in a type of compound produced within the stomach called intrinsic factor (a type of glycoprotein), which combines with vitamin B12 once consumed in order to allow it to be absorbed
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Feeling the scale of it as treatment begins is part of that picture
For patients on established B12 injection therapy, monitoring is based primarily on clinical response and haematological parameters rather than routine serum B12 measurements, which may remain very high without indicating harm or overtreatment
Accessed December 8, 2022
Health Canada has issued parallel advisories on unauthorized injectable peptide products, and no AOD-9604 preparation is authorized for compounding in Canada either